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Setmelanotide 结构式

Setmelanotide

仅供科学研究,不可用于个人用途。
CAS号:920014-72-8
产品编号:BCP42295 纯度:98%
分子式:C49H68N18O9S2 分子量:1117.32
英文名:Setmelanotide
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  • 基本信息
  • 产品描述
  • 质检证书
中文名称 司美诺肽
英文名称 Setmelanotide
中文别名 RM-493; RM493; RM 493; BIM-22493; BIM22493; BIM 22493; IRC-022493; IRC 022493; IRC022493
英文别名 RM-493; RM493; RM 493; BIM-22493; BIM22493; BIM 22493; IRC-022493; IRC 022493; IRC022493
CAS号 920014-72-8
产品编号 BCP42295
纯度 98%
分子量 1117.32
分子式 C49H68N18O9S2
储存条件 Store at 4-8°C
配送 惯例下常温包邮(中国大陆地区)
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other earlier treatments for these patients included gastric bypass surgery. Patients taking setmelanotide experienced an average weight loss of 0.6 kg/week. Imcivree was granted EMA orphan designation on 19 November 2018 and FDA approval on 25 November 2020.

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