SLx-4090 新
仅供科学研究，不可用于个人用途。
即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| 中文名称 | SLx-4090 |
| 英文名称 | SLx-4090 |
| 中文别名 | KD-026; KD026; KD 026; SLx 4090; SLx4090 |
| 英文别名 | KD-026; KD026; KD 026; SLx 4090; SLx4090 |
| CAS号 | 913541-47-6 |
| 产品编号 | BCP45940 |
| 纯度 | 98% |
| 分子量 | 546.54 |
| 分子式 | C31H25F3N2O4 |
| 储存条件 | Store at 4-8°C |
| 配送 | 惯例下常温包邮（中国大陆地区） |
SLx-4090 is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes. SLx-4090 (IC(50 ∼8 nM) was designed to inhibit only MTP localized to enterocytes. In Caco-2 cells SLx-4090 inhibited apolipoprotein B (IC50 ∼9.6 nM) but not apolipoprotein A1 secretion. Administered orally to rats SLx-4090 reduced postprandial lipids by >50% with an ED(50) value ∼7 mg/kg. Chronic treatment with SLx-4090 in mice maintained on a high-fat diet decreased LDL-C and TG and resulted in weight loss without the elevation of liver enzymes or an increase in hepatic fat. The compound did not result in toxicity when administered to rats for 90 days at a dose of 1000 mg/kg per day.
Tags:SLx-4090 供应商,SLx-4090 购买,SLx-4090 生产,SLx-4090 批量,SLx-4090 供应,SLx-4090 订购,SLx-4090 采购
联系方式
