SBI-425 新
仅供科学研究,不可用于个人用途。
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中文名称 | SBI-425 |
英文名称 | SBI-425 |
中文别名 | SBI425;SBI 425 |
英文别名 | SBI425;SBI 425 |
CAS号 | 1451272-71-1 |
产品编号 | BCP45955 |
纯度 | 98% |
分子量 | 341.77 |
分子式 | C13H12ClN3O4S |
储存条件 | Store at 4-8°C |
配送 | 惯例下常温包邮(中国大陆地区) |
SBI-425 is a potent, selective and oral bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP) with an IC50 value of 0.016 μM. SBI-425 robustly inhibits TNAP in vivo after oral dosing. Furthermore, SBI-425 demonstrated activity in blocking calcification in patient derived fibroblasts as well as in rodent models of GACI and PXE.
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