AS-2444697 HCl 新
仅供科学研究，不可用于个人用途。
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| 中文名称 | AS-2444697 HCl |
| 英文名称 | AS-2444697 HCl |
| 中文别名 | AS-2444697; AS 2444697; AS2444697; AS-2444697 hydrochloride |
| 英文别名 | AS-2444697; AS 2444697; AS2444697; AS-2444697 hydrochloride |
| CAS号 | 1287665-60-4 |
| 产品编号 | BCP45939 |
| 纯度 | 98% |
| 分子量 | 432.86 |
| 分子式 | C19H21ClN6O4 |
| 储存条件 | Store at 4-8°C |
| 配送 | 惯例下常温包邮（中国大陆地区） |
AS-2444697 is a RAK-4 inhibitor. Six weeks' repeated administration of AS2444697 (0.3-3 mg/kg, twice daily) dose-dependently and significantly reduced urinary protein excretion and prevented the development of glomerulosclerosis and interstitial fibrosis without affecting the blood pressure. AS2444697 significantly reduced or showed a decreasing trend in expression and levels of these inflammatory parameters. AS2444697 suppresses the progression of chronic renal failure via anti-inflammatory action and may therefore be potentially useful in treating CKD patients.
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