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Istaroxime 结构式

Istaroxime

仅供科学研究,不可用于个人用途。
CAS号:1234319-68-6
产品编号:BCP44936 纯度:98%
分子式:C58H80N16O14 分子量:1225.36
英文名:Istaroxime
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  • 基本信息
  • 产品描述
  • 质检证书
中文名称 Istaroxime
英文名称 Istaroxime
中文别名 TAK448;TAK 448;TAK-448
英文别名 TAK448;TAK 448;TAK-448
CAS号 1234319-68-6
产品编号 BCP44936
纯度 98%
分子量 1225.36
分子式 C58H80N16O14
储存条件 Store at 4-8°C
配送 惯例下常温包邮(中国大陆地区)
TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints.

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